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An Improved Method for Visualization of Multidimensional Data ("Logicle")


Stanford Reference:

02-263


Abstract


Researchers at Stanford have developed a method that provides improved displays for flow cytometry data and similar data types (usually multidimensional) to promote correct and accurate interpretation of the information contained therein.

Stanford is not asserting the patent in the field of flow cytometry.

Applications


  • Method of analyzing data using a computer, including using the scaled data to identify portions of the raw data of interest
  • Methods of this invention can be implemented in a localized or distributed computing environment

Advantages


  • The data scaling is specified by a mathematically well-defined function which can be readily computed
  • Ability to optimize display of particular data sets
  • The linear to logarithmic transition is very smooth, minimizing the likelihood that display artifacts will be created
  • The method retains a rectilinear display grid (lines of equal signal level are straight and horizontal or vertical)

Publications


  • Leonore A Herzenberg, James Tung, Wayne A Moore, Leonard A Herzenberg & David R Parks. Interpreting flow cytometry data: a guide for the perplexed. Nature Immunology 7, 681 - 685 (2006).
  • Parks DR, Roederer M, Moore WA. A new "Logicle" display method avoids deceptive effects of logarithmic scaling for low signals and compensated data. Cytometry A. 2006 Jun;69(6):541-51.
  • See below for the issued U.S. Patent.

Non-assert for patent in field of flow cytometry


Stanford will not assert U.S. patent 6,954,722 in the field of flow cytometry.

Innovators & Portfolio



Patent Status



Date Released

 3/26/2004 12:00
 

Licensing Contact


Cheryl Cathey, Senior Licensing and Strategic Alliance Manager
(650) 724-0960 (Direct)
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Related Keywords


genomics   PS: software: data management   research tool   Computer: software   Computer