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endothelial derived lipase (EDL) knockout mouse


Stanford Reference:

03-321


Abstract


EDL (gene nomenclature, LIPG; protein, EL), gene targeted, mouse bred to homozygosity for the purposes of biological studying of EDL and the role it plays in lipoprotein metabolism. The data recovered from the experiment shows that EL does make a physiological contribution to HDL metabolism in mice and possibly in humans as well, granted EL in humans and mice maintain similar roles.

Publication: The Journal of Clinical Investigation, Feb.2003, Vol 111, No.3.



Applications


  • To Study biology of EDL, and the role it plays in lipoprotein metabolism.

Publications



Innovators & Portfolio


  • Tatsuro Ishida   
  • Thomas Quertermous   

Date Released

 6/24/2004 12:00
 

Licensing Contact


Agreements Group
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82-008 A Monoclonal Antibody Specific For Mouse Granulocytes - RB6-8C5 and RA3-6B2
82-010 A Monoclonal Antibody Specific for the B-220 Surface Glycoprotein in Mouse (RA3-3A1)
82-011 A Monoclonal Antibody Specific for Mouse and Human B Cells

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Related Keywords


research tool   cardiovascular   LS: research tool: animal model