Scintillation Crystal Detection Arrays for Radiation Imaging Devices

Stanford Reference:

04-235

Abstract

A Stanford researcher has developed two advanced approaches for the positron sensitive high-energy photon sensor technology for Positron Emission Tomography (PET). In the first approach, the radiation imaging device comprises layers of very thin position sensitive scintillation detectors that provide high scintillation light collection efficiency independent of interaction location, directly measured the interaction depth of the photons within thick detection volume, and 3D positional, energy, and temporal information for each interaction in multi-interaction photon events. The benefit of this improved device is that it simultaneously facilitates high spatial resolution, high 511 keV photon absorption efficiency, high scintillation light collection efficiency, and accurate photon interaction depth measurement without compromising performance parameters important for PET.

Applications

Nuclear Medicine--PET, SPECT
Molecular Imaging
Photo Imaging
Spectroscopy
Astrophysics
Security Screening
Radiation Detection/Imaging
Homeland Defense
Mineral Exploration

Advantages

Uniform and ultra-high spatial resolution
Enhance high photon detection efficiency
High signal-to-noise ratio
Excellent energy resolution for high image contrast and quantitative accuracy of image data
Compatible with other imaging modalities for multi-modality platforms

Publications

Levin CS (2002) "Design of a High-Resolution and High Sensitivity Scintillation Crystal Array with Nearly Perfect Light Collection". IEEE Transactions on Nuclear Science, 49, pp. 2236-43.
Foudray AMK, Habte F, Levin CS, Olcott PD (2006) "Positioning Annihilation Photon Interactions in a Thin LSO Crystal Sheet with a Position-Sensitive Avalanche Photodiodes". IEEE Transactions on Nuclear Science, 53, pp. 2549-2556.
Levin CS, Habte F, Foudray AMK, Chang J, Chinn G (2006) "Impact of High Energy Resolution Detectors on the Performance of a PET System Dedicated to Breast Cancer Imaging". Physica Medica, 21, pp. 28-34.
Zhang J, Olcott PD, Levin CS (2007) "A New Positioning Algorithm for Position-Sensitive Avalanche Photodiodes". IEEE Transactions on Nuclear Science, 54, pp. 433-437.
Zhang J, Foudray AMK, Olcott PD, Levin CS (2007) "Performance Characterization of a Novel Thin Position-Sensitive Avalanche Photodiode for High Resolution Positron Emission Tomography". IEEE Transactions on Nuclear Science, 54, pp. 415-421.
Habte F, Foudray AMK, Olcott PD, Levin CS (2007) "Effects of System Geometry and Other Physical Factors on Photon Sensitivity of High Resolution Positron Emission Tomography". Physics in Medicine and Biology, 52 pp. 3753-3772.
Levin CS (2008) "New Imaging Technologies to Enhance the Molecular Sensitivity of Positron Emission Tomography". Proceedings of the IEEE, 96, pp. 439-67.
Pratx G, Levin CS (2009) "Bayesian reconstruction of photon interaction sequences for high-resolution PET detectors". Physics in Medicine and Biology, 54, pp. 5073-5094.
Peng H, Levin CS (2010) "Design study of a high-resolution breast-dedicated PET system built from cadmium zinc telluride detectors". Physics in Medicine and Biology, 55, pp. 2761-2788.

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Patent Status

Date Released

9/6/2018 12:00

Licensing Contact

David Mallin, Licensing Manager, Physical Sciences
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Related Keywords

MD: imaging: CT (computed tomography) MD: imaging: PET (positron emission tomography) MD: imaging: all modalities imaging: molecular PS: photonics: scintillation detector diagnostic: detection PS: instrumentation: photon detector radiography radioimaging healthcare: X-Ray particle detection PS: semiconductor: devices PS: semiconductor: optical single photon emission computed tomography x-ray detection

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