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Interpenetrating Network Hydrogels and their Photochemical Modification
Stanford Reference:
07-019
Abstract
An interdisciplinary team of Stanford University researchers have developed a novel interpenetrating polymer network hydrogel that is useful for a wide variety of medical, industrial and personal hygiene applications. The material is simultaneously mechanically strong, biocompatible, and highly water-absorbent. In addition, surface modifications can be used to attach biomolecules to the hydrogel.
Applications
Ophthalmic Implants
Advantages
Mechanically strong
- high tensile and compressive strength
Low coefficient of friction
- high surface lubricity
Hydrophilic:
60 - 90% water content
high swellability
High permeability
Optical transparency
Biocompatibility
Publications
Tan XW et al.
In vivo biocompatibility of two PEG/PAA interpenetrating polymer networks as corneal inlays following deep stromal pocket implantation.
J Mater Sci Mater Med
2013 Apr; 24(4):967-977.
Myung D, Koh W, Bakri A, Zhang F, Marshall A, Ko J, Noolandi J, Carrasco M, Cochran JR, Frank CW, Ta CN,
"Design and fabrication of an artificial cornea based on a photolithographically patterned hydrogel construct."
Biomed Microdevices
2007 Jan 20.
Related Web Links
Artificial Cornea Research Group
Innovators & Portfolio
Curtis Frank
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Laura Hartmann
David Myung
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Jaan Noolandi
Christopher Ta
Patent Status
Published Application: 20080269370
Issued : 8,821,583 (USA)
Date Released
4/25/2016 12:00
Licensing Contact
Irit Gal, Senior Licensing Manager
650-723-1586 (Business)
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Related Keywords
LS: General Therapeutic: Ophthalmology
PS: materials: polymers
artificial organs
MD: Wound Management: Hydrogel