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Population Clustering for Analyzing Flow Cytometry and Other Large Data Sets
Stanford Reference:
02-215
Abstract
This patented, automated data analytics tool sorts and analyzes large data sets by identifying and creating clusters of data. The algorithm intakes data and then groups them into clusters, groupings, or populations of data. This nonparametric method has been used for identifying homogenous subpopulations of cells (i.e. gating) in flow cytometry data. The technique is also broadly applicable for data analysis in any other field that contains clusterable parameters, such as marketing, data mining, genomics, or financial software.
Applications
Flow cytometry analysis - gating to identify subpopulations of cells
Data analysis for:
Market research
Genomics - gene expression, functional genomics
Data mining
Financial software
Advantages
Automated and objective - not subject to user’s interpretation and experience
Fast - automatic gating for flow cytometry takes a fraction of a second
Non-parametric - can reproduce nonconvex subpopulations
Publications
Walther G, Zimmerman N, Moore W, Parks D, Meehan S, Belitskaya I, Pan J, Herzenberg L.,
"Automatic clustering of flow cytometry data with density-based merging."
Adv Bioinformatics.
2009:686759. Epub 2009 Nov 19.
Innovators & Portfolio
Ilana Belitskaya
Leonore Herzenberg
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Wayne Moore
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Jinhui Pan
David Parks
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Guenther Walther
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Patent Status
Published Application: 20110029519
Published Application: 20130246434
Issued : 8,473,215 (USA)
Issued : 9,552,416 (USA)
Date Released
7/11/2011 12:00
Licensing Contact
Imelda Oropeza, Senior Licensing Manager, Physcial Sciences
650-725-9039 (Business)
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Related Keywords
FACS (Fluorescent Activated Cell Sorting)
analytics software
data analysis software
data analytics
flow cytometry software
genomics: bioinformatic
genomics: microarray software
high-dimensional data analysis
microarray software
software: bioinformatics
sequence analysis software
statistical analysis software
big data
bioinformatics
PS: software: data mining
PS: software: lab management