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Hybrid Referenceless and Multibaseline PRF-Shift MR Thermometry
Stanford Reference:
09-379
Abstract
Researchers at Stanford University have developed a more accurate method for estimating temperatures in the heart during thermal therapies such as cardiac ablation. This new method is a hybrid, combining the strengths of referenceless and multi-baseline thermometry to subtract the effects of heart motion and respiration while providing a temperature estimate with a low margin of error.
Applications
Medical monitoring
- used to monitor thermal therapies, such as ablation, during cardiac procedures
Advantages
Greater accuracy
- estimates temperature with much lower error than techniques based on multi-baseline subtraction or referenceless methods alone
Simple
- requires no gating navigator acquisitions or susceptibility modeling
Publications
Grissom WA, Rieke V, Holbrook AB, Medan Y, Lustig M, Santos J, McConnell MV, Pauly KB.
Hybrid referenceless and multibaseline subtraction MR thermometry for monitoring thermal therapies in moving organs.
Med Phys. 2010 Sep;37(9):5014-26.
U.S. Patent Application Nos.
13/009,209
and
13/009,318
Stage of Research
The innovators have demonstrated that this method estimates temperature with much lower error in the left ventricular myocardium of a volunteer, compared to multi-baseline subtraction and referenceless methods alone.
Innovators & Portfolio
Kim Butts Pauly
more technologies from Kim Butts Pauly »
William Grissom
Yoav Levy
Michael Lustig
more technologies from Michael Lustig »
Yoav Medan
Viola Rieke
Patent Status
Published Application: 20110175615
Published Application: WO2011090990
Published Application: 20110178386
Issued : 8,810,246 (USA)
Issued : 8,482,285 (USA)
Date Released
5/13/2011 12:00
Licensing Contact
Jon Gortat, Licensing & Strategic Alliances Director for Physical Science
219.746.3419 cell
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Related Keywords
LS: consumer products: physiological monitoring
patient monitoring
cardiovascular
cardiac rhythm management
MD: cardiovascular: ablation
algorithm
